The Greek side had won their last eight games in the competition but were finally beaten 77-73 by their Group C rivals on Tuesday.
However, they can still celebrate progression from the group stage after Lietkabelis lost 78-71 to CEZ Nymburk and Montakit Fuenlabrada slumped to a 73-59 defeat to JDA Dijon, those results keeping them five points clear of the bottom four sides in the eight-team group, with AEK guaranteed at least four more points.
Iberostar Tenerife, champions in 2017, are not quite sure of a playoff spot despite a 72-66 victory over Fribourg Olympic, Davin White helping them win it in the final minute and Colton Iverson tallying 23 points and 11 rebounds in his first Champions League double-double.
They lead Group B from Umana Reyer Venezia, who eased to a 102-81 win over Opava, while PAOK brushed aside UNET Holon 92-77.
SIG Strasbourg’s hopes in a tight Group D were dented by a 69-64 defeat to Besiktas Sompo Japan, who were led by 28 points from Jason Rich. Elsewhere, in Group A Sidigas Avellino came through 72-62 against Anwil to bolster their playoff aspirations.
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